Plaque Research Today is a free monthly online journal that collates and summarizes the latest research about Plaque, including details on dentistry, brushing, oral hygiene, mouthwash.

Intraoral delivery of antimicrobials.

Raj PA, Dentino AR

Division of Periodontics and Department of Surgical Sciences, School of Dentistry, Marquette University, Milwaukee, Wisconsin 53201, USA.

Antimicrobial therapies for oral diseases have been in use for centuries, but have undergone rapid changes in the last decade. In the coming years, antimicrobial strategies will become more sophisticated and efficacy will be greatly improved as new therapeutic technologies emerge. New delivery systems for common antimicrobials and novel agents to modulate the immune system, as well as biofilm formation and maturation, may be on the horizon. This review describes the development and the application of intraoral antimicrobial drug delivery in the oral environment. Current clinical uses of antimicrobials as well as future approaches to the treatment and prevention of oral infectious diseases are discussed.

Published 25 October 2005 in Drug News Perspect, 18(6): 362-74.
Full-text of this article is available online (may require subscription).

© 2004-2008 Plaque Research Today. All Rights Reserved.